We develop quantitative light microscopy and numerical models of cytoskeleton mechanics to study the molecular regulation of cell migration and chromosome segregation in normal physiology and disease.
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Jaqaman K., Loerke D., Mettlen M., Kuwata H., Grinstein S., Schmid S.L., Danuser G.
Robust single-particle tracking in live-cell time-lapse sequences.
Nature Methods 5:695-702. 2008